FLCN

folliculin
OMIM: 607273, Gene2Phenotype

13 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 13 panels
Green FLCN in Renal cancer pertinent cancer susceptibility Level 3: Pertinent cancer susceptibility gene panel Level 2: Cancer Programme Version 1.2	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Expert list Phenotypes Renal cancer
Green FLCN in Adult solid tumours for rare disease Level 3: Tumour syndromes Level 2: Tumour syndromes Version 1.40	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert list Expert Review Green Phenotypes renal oncocytoma
Red FLCN in Familial pulmonary fibrosis Level 3: Interstitial lung disorders Level 2: Respiratory disorders Version 1.31	review	Not set	Sources Expert Review Red Emory Genetics Laboratory Phenotypes Pulmonary Disease
Green FLCN in Pneumothorax - familial Level 3: Structural lung disorders Level 2: Respiratory disorders Version 3.5 Latest signed off version: v3.0 (22 Mar 2023)	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources NHS GMS Eligibility statement prior genetic testing Expert Review Green UKGTN Emory Genetics Laboratory Illumina TruGenome Clinical Sequencing Services Radboud University Medical Center, Nijmegen Expert list Literature Phenotypes Pneumothorax, primary spontaneous, OMIM:173600 Birt-Hogg-Dube Syndrome, OMIM:135150 Tags deletions
Green FLCN in Inherited renal cancer Version 1.27 Latest signed off version: v1.2 (4 Mar 2020)	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Expert List UKGTN Phenotypes Birt-Hogg-Dube syndrome, OMIM:135150 Renal carcinoma, MONDO:0005206
Green FLCN in Cystic kidney disease Level 3: Structural renal and urinary tract disease Level 2: Renal and urinary tract disorders Version 4.24 Latest signed off version: v4.0 (22 Mar 2023) Component of the following Super Panels: Cystic renal disease Renal superpanel - broad Renal superpanel - narrow	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Expert Review Literature Phenotypes Birt-Hogg-Dube syndrome, OMIM:135150 renal cysts cutaneous fibrofolliculoma pneumothorax pulmonary cysts renal cell carcinoma renal oncocytoma
Green FLCN in Multiple monogenic benign skin tumours Version 2.4 Latest signed off version: v2.0 (30 Nov 2022)	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources London North GLH NHS GMS Expert Review Green Phenotypes Birt-Hogg-Dub syndrome, OMIM:135150
Green FLCN in Adult solid tumours cancer susceptibility Level 3: Pertinent cancer susceptibility gene panel Level 2: Cancer Programme Version 2.29 Latest signed off version: v2.2 (18 Feb 2020)	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources NHS GMS Expert Review Green Expert list Phenotypes renal oncocytoma
Red FLCN in Thoracic aortic aneurysm or dissection (GMS) Version 3.11 Latest signed off version: v3.0 (22 Mar 2023)	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Red NHS GMS South West GLH London South GLH South West GLH London South GLH Phenotypes Birt-Hogg-Dube syndrome,135150 Pneumothorax, primary spontaneous, 173600
Green FLCN in Thoracic aortic aneurysm or dissection Level 3: Connective tissue disorders and aortopathies Level 2: Cardiovascular disorders Version 1.127	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources South West GLH London South GLH UKGTN Illumina TruGenome Clinical Sequencing Services Emory Genetics Laboratory Phenotypes Pneumothorax, primary spontaneous, 173600 Birt-Hogg-Dube syndrome,135150
Amber FLCN in Unexplained young onset end-stage renal disease Version 3.40 Latest signed off version: v3.0 (22 Mar 2023) Component of the following Super Panels: Renal superpanel - broad	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources NHS GMS Expert Review Amber Phenotypes Birt-Hogg-Dube syndrome, OMIM:135150 renal cell carcinoma renal cysts pneumothorax renal oncocytoma pulmonary cysts cutaneous fibrofolliculoma Tags Q4_23_promote_green
Red FLCN in Ehlers Danlos syndrome with a likely monogenic cause Level 3: Connective tissues disorders Level 2: Rheumatological disorders Version 3.12 Latest signed off version: v3.0 (22 Mar 2023)	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Red Emory Genetics Laboratory Phenotypes Pneumothorax, primary spontaneous, 173600 Connective Tissue Disorders
Green FLCN in Severe Paediatric Disorders Version 1.184	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Next Generation Children Project Expert Review Green Expert list Phenotypes Pneumothorax, primary spontaneous, 173600 Birt-Hogg-Dube syndrome, 135150