FLCN

folliculin
OMIM: 607273, Gene2Phenotype

12 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 12 panels
Green FLCN in Renal cancer pertinent cancer susceptibility Level 3: Pertinent cancer susceptibility gene panel Level 2: Cancer Programme Version 1.3	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Expert list Phenotypes Renal cancer
Green FLCN in Adult solid tumours for rare disease Level 3: Tumour syndromes Level 2: Tumour syndromes Version 1.42	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert list Expert Review Green Phenotypes renal oncocytoma
Red FLCN in Familial pulmonary fibrosis Level 3: Interstitial lung disorders Level 2: Respiratory disorders Version 1.32	review	Not set	Sources Expert Review Red Emory Genetics Laboratory Phenotypes Pulmonary Disease
Green FLCN in Pneumothorax - familial Level 2: Respiratory Version 3.6 Latest signed off version: v3.0 (22 Mar 2023)	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources NHS GMS Eligibility statement prior genetic testing Expert Review Green UKGTN Emory Genetics Laboratory Illumina TruGenome Clinical Sequencing Services Radboud University Medical Center, Nijmegen Expert list Literature Phenotypes Pneumothorax, primary spontaneous, OMIM:173600 Birt-Hogg-Dube Syndrome, OMIM:135150 Tags deletions
Green FLCN in Inherited renal cancer Level 2: Inherited cancer Version 1.28 Latest signed off version: v1.2 (4 Mar 2020)	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Expert List UKGTN Phenotypes Birt-Hogg-Dube syndrome, OMIM:135150 Renal carcinoma, MONDO:0005206
Green FLCN in Cystic kidney disease Level 2: Renal Version 8.5 Latest signed off version: v8.0 (30 Apr 2025) Component of the following Super Panels: Cystic renal disease Unexplained young onset end-stage renal disease	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Expert Review Literature Phenotypes Birt-Hogg-Dube syndrome, OMIM:135150 renal cysts cutaneous fibrofolliculoma pneumothorax pulmonary cysts renal cell carcinoma renal oncocytoma
Green FLCN in Multiple monogenic benign skin tumours Level 2: Dermatology Version 2.5 Latest signed off version: v2.0 (30 Nov 2022)	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources London North GLH NHS GMS Expert Review Green Phenotypes Birt-Hogg-Dub syndrome, OMIM:135150
Green FLCN in Adult solid tumours cancer susceptibility Level 2: Cancer susceptibility Version 2.35 Latest signed off version: v2.2 (18 Feb 2020)	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources NHS GMS Expert Review Green Expert list Phenotypes renal oncocytoma
Red FLCN in Thoracic aortic aneurysm or dissection (GMS) Level 2: Cardiology Version 4.5 Latest signed off version: v4.0 (30 Apr 2025)	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Red NHS GMS South West GLH London South GLH South West GLH London South GLH Phenotypes Birt-Hogg-Dube syndrome,135150 Pneumothorax, primary spontaneous, 173600
Green FLCN in Thoracic aortic aneurysm or dissection Level 3: Connective tissue disorders and aortopathies Level 2: Cardiovascular disorders Version 1.129	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources South West GLH London South GLH Illumina TruGenome Clinical Sequencing Services UKGTN Emory Genetics Laboratory Phenotypes Pneumothorax, primary spontaneous, 173600 Birt-Hogg-Dube syndrome,135150
Red FLCN in Ehlers Danlos syndrome with a likely monogenic cause Level 2: Musculoskeletal Version 4.6 Latest signed off version: v4.0 (30 Apr 2025)	review	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Red Emory Genetics Laboratory Phenotypes Pneumothorax, primary spontaneous, 173600 Connective Tissue Disorders
Red FLCN in Fetal anomalies Level 2: Fetal (including NIPD) Version 6.140 Latest signed off version: v6.0 (30 Apr 2025)	review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Red NHS GMS Phenotypes Birt-Hogg-Dube syndrome, 135150 Pneumothorax, primary spontaneous, OMIM:173600