Combined B and T cell defect
Gene: LIG4
Comment on list classification: Originally a green gene, and 3 reviewers agree.Created: 3 Jun 2016, 12:45 p.m.
This gene has been classified as Green List (High Evidence).
This gene has been classified as Green List (High Evidence).
Phenotypes for LIG4 were set to LIG4 syndrome, 606593{Multiple myeloma, resistance to}, 254500; Severe combined immunodeficiency with sensitivity to ionizing radiation, 602450; Severe Combined Immunodeficiency with Sensitivity to Ionizing Radiation; T-B- SCID; T-B+ SCID
Model of inheritance for gene LIG4 was changed to BIALLELIC, autosomal or pseudoautosomal
LIG4 was added to Combined B and T cell defectpanel. Sources: Radboud University Medical Center, Nijmegen,Emory Genetics Laboratory,Illumina TruGenome Clinical Sequencing Services,UKGTN
Model of inheritance for gene LIG4 was changed to BIALLELIC, autosomal or pseudoautosomal
LIG4 was added to Combined B and T cell defectpanel. Sources: Radboud University Medical Center, Nijmegen,Emory Genetics Laboratory,Illumina TruGenome Clinical Sequencing Services,UKGTN
Model of inheritance for gene LIG4 was changed to BIALLELIC, autosomal or pseudoautosomal
LIG4 was added to Combined B and T cell defectpanel. Sources: Radboud University Medical Center, Nijmegen,Emory Genetics Laboratory,Illumina TruGenome Clinical Sequencing Services,UKGTN
LIG4 was added to Combined B and T cell defectpanel. Sources: Radboud University Medical Center, Nijmegen,Emory Genetics Laboratory,Illumina TruGenome Clinical Sequencing Services,UKGTN