Monogenic hearing loss
Gene: STRCNew review confirms gene status and mode of inheritance; no changes required.Created: 1 Jun 2018, 2:31 p.m.
Possible pseudogene interferenceCreated: 10 Apr 2018, 4:27 p.m.
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
#603720:Deafness, autosomal recessive 16[Hearing loss, sensorineural, mild to moderateHigh frequency sloping audiometric profile]
Publications
Comment on list classification: Good evidence from expert reviewer and OMIMCreated: 31 Jan 2016, 8 p.m.
Definitely a deafness gene but also a PSEUDOGENE as well, so difficult to reportCreated: 19 Oct 2015, 6:12 p.m.
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Variants in this GENE are reported as part of current diagnostic practice
Publications for STRC were set to PMID:11687802; 12434312; 12825070; 17098888; 18849963; 22147502; 26011646
Mode of inheritance for STRC was changed to BIALLELIC, autosomal or pseudoautosomal
This gene has been classified as Green List (High Evidence).
This gene has been classified as Green List (High Evidence).
STRC was added to Congenital hearing impairment (Profound/Severe)panel. Sources: UKGTN,Radboud University Medical Center, Nijmegen,Expert
STRC was added to Congenital hearing impairment (Profound/Severe)panel. Sources: UKGTN,Radboud University Medical Center, Nijmegen,Expert
STRC was added to Congenital hearing impairment (Profound/Severe)panel. Sources: UKGTN,Radboud University Medical Center, Nijmegen,Expert