1. Panels
  2. Dilated Cardiomyopathy (DCM)
  3. TMPO
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Dilated Cardiomyopathy (DCM)

Gene: TMPO

Red List (low evidence)
TMPO (thymopoietin)
EnsemblGeneIds (GRCh38): ENSG00000120802
EnsemblGeneIds (GRCh37): ENSG00000120802
OMIM: 188380, Gene2Phenotype
TMPO is in 3 panels

2 reviews

Rebecca Foulger (Genomics England curator)

Comment on list classification: Changed rating from Amber to Red based on new evidence in OMIM: The variant R690C, formerly designated CARDIOMYOPATHY, DILATED, 1T, has been reclassified as a VARIANT OF UNKNOWN SIGNIFICANCE.
Created: 11 May 2017, 9:40 a.m.
Created: 11 May 2017, 9:40 a.m.

Panel version: 1.29

Oxford Medical Genetics Laboratory (OUH NHS Foundation Trust)

I don't know

Created: 6 Jan 2016, 5:12 p.m.

Panel version: 0.3

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Red
  • UKGTN
  • Expert list
  • Illumina TruGenome Clinical Sequencing Services
Phenotypes
  • Dilated Cardiomyopathy, Dominant
OMIM
188380
Clinvar variants
Variants in TMPO
Penetrance
Complete
Panels with this gene

History Filter Activity

11 May 2017, Gel status: 1

Gene classified by Genomics England curator

Rebecca Foulger (Genomics England curator)

This gene has been classified as Red List (Low Evidence).

13 Jul 2015, Gel status: 2

Added New Source

Ellen McDonagh (Genomics England Curator)

TMPO was added to Dilated Cardiomyopathy (DCM)panel. Sources: UKGTN

13 Jul 2015, Gel status: 1

Set Mode of Inheritance

Ellen McDonagh (Genomics England Curator)

Model of inheritance for gene TMPO was changed to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

13 Jul 2015, Gel status: 1

Added New Source

Ellen McDonagh (Genomics England Curator)

TMPO was added to Dilated Cardiomyopathy (DCM)panel. Sources: Illumina TruGenome Clinical Sequencing Services,Expert list

13 Jul 2015, Gel status: 1

Added New Source

Ellen McDonagh (Genomics England Curator)

TMPO was added to Dilated Cardiomyopathy (DCM)panel. Sources: Illumina TruGenome Clinical Sequencing Services,Expert list