Deafness and congenital structural abnormalities
Gene: WIF1EnsemblGeneIds (GRCh38): ENSG00000156076
EnsemblGeneIds (GRCh37): ENSG00000156076
OMIM: 605186, Gene2Phenotype
WIF1 is in 1 panel
5 reviews
Muriel Holder (Clinical Genetics, Guy's Hospital)
Mode of inheritance
Unknown
Mode of pathogenicity
Other
Sarah Leigh (Genomics England Curator)
Not associated with phenotype in OMIM or G2P / DD. No variants reportedCreated: 20 Sep 2016, 7:21 a.m.
Mode of inheritance
Unknown
Ellen McDonagh (Genomics England Curator)
Comment on list classification: Red on the Bilateral Microtia Version 1.10 panel.Created: 12 Sep 2016, 3:02 p.m.
Jun Shen (Harvard Medical School)
WIF1 is not associated with a phenotype entry in OMIM.Created: 9 Feb 2016, 5:16 p.m.
Publications
- PMID:10201374
Maria Bitner-Glindzicz (UCL)
Details
- Mode of Inheritance
- Unknown
- Sources
-
- Expert Review Red
- Expert list
- Phenotypes
-
- Bilateral Microtia
- OMIM
- 605186
- Clinvar variants
- Variants in WIF1
- Penetrance
- Complete
- Panels with this gene
History Filter Activity
panel promoted to version 1
Ellen McDonagh (Genomics England Curator)26th Oct 2016: the panels Bilateral microtia version 1.10, Ear malformations with hearing impairment version 0.105, and familial hemifacial microsomia version 0.149 gene panels were combined to create this panel. The panel was revised due to expert review, further curation of evidence and internal clinical evaluation. Ready for promotion to version 1.
Gene classified by Genomics England curator
Ellen McDonagh (Genomics England Curator)This gene has been classified as Red List (Low Evidence).
Set Mode of Inheritance
Sarah Leigh (Genomics England Curator)Model of inheritance for gene WIF1 was set to Unknown
Created
Sarah Leigh (Genomics England Curator)WIF1 was created by sleigh
Added New Source
Sarah Leigh (Genomics England Curator)WIF1 was added to Deafness and congenital structural abnormalitiespanel. Sources: Expert list,Expert Review Red