This Panel is marked as Internal
DNA Repair Genes pertinent cancer susceptibility
Gene: MUTYH
MUTYH (mutY DNA glycosylase)
EnsemblGeneIds (GRCh38): ENSG00000132781
EnsemblGeneIds (GRCh37): ENSG00000132781
OMIM: 604933, Gene2Phenotype
MUTYH is in 10 panels
EnsemblGeneIds (GRCh38): ENSG00000132781
EnsemblGeneIds (GRCh37): ENSG00000132781
OMIM: 604933, Gene2Phenotype
MUTYH is in 10 panels
0 reviews
Details
- Sources
-
- Human DNA Repair Genes Database
- Phenotypes
-
- Class: Base excision repair (BER)
- DNA glycosylases, major altered base released:A opposite 8-oxoG
- OMIM
- 604933
- Clinvar variants
- Variants in MUTYH
- Penetrance
- Complete
- Panels with this gene
-
- Colorectal cancer pertinent cancer susceptibility
- Adult solid tumours for rare disease
- Familial breast cancer
- Additional findings health related - CNV analysis adult specific
- GI tract tumours
- Additional findings health related - adult specific
- Adult solid tumours cancer susceptibility
- Inherited ovarian cancer (without breast cancer)
- Additional findings health related
- Inherited polyposis and early onset colorectal cancer - germline testing
History Filter Activity
7 Sep 2018, Gel status: 1
Panel promoted to version 1.0
Louise Daugherty (Genomics England Curator)Louise Daugherty: MRE11 approved gene symbol in
21 Jun 2017, Gel status: 0
Created
Ellen McDonagh (Genomics England Curator)MUTYH was created by ellenmcdonagh
21 Jun 2017, Gel status: 0
Added New Source
Ellen McDonagh (Genomics England Curator)MUTYH was added to DNA Repair Genespanel. Sources: Human DNA Repair Genes Database