Amyotrophic lateral sclerosis/motor neuron disease
Gene: FUS
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
This gene is on the ALS/MND NGS Panel in the UCLH National Hospital for Neurology and Neurosurgery & Institute of Neurology (NHNN) Neurogenetics genetic testing manual.Created: 13 Jun 2016, 9:11 a.m.
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
familial amyotrophic lateral sclerosis (ALS6)
Comment when marking as ready: Lots of cases in literature, OMIM and ClinVarCreated: 10 May 2016, 1:43 p.m.
Promoted to version 1 on 19th December 2016 following external review and internal curation
This gene has been classified as Green List (High Evidence).
Model of inheritance for gene FUS was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
FUS was added to Amyotrophic lateral sclerosis/motor neuron diseasepanel. Source: Expert
Model of inheritance for gene FUS was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
FUS was added to Amyotrophic lateral sclerosis/motor neuron diseasepanel. Source: Illumina TruGenome Clinical Sequencing Services
Model of inheritance for gene FUS was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
FUS was added to Amyotrophic lateral sclerosis/motor neuron diseasepanel. Source: UKGTN
Model of inheritance for gene FUS was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
FUS was added to Amyotrophic lateral sclerosis/motor neuron diseasepanel. Source: Radboud University Medical Center, Nijmegen
Model of inheritance for gene FUS was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
FUS was added to Amyotrophic lateral sclerosis/motor neuron diseasepanel. Source: Expert
Model of inheritance for gene FUS was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
FUS was added to Amyotrophic lateral sclerosis/motor neuron diseasepanel. Source: Illumina TruGenome Clinical Sequencing Services
Model of inheritance for gene FUS was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
FUS was added to Amyotrophic lateral sclerosis/motor neuron diseasepanel. Source: UKGTN
FUS was added to Amyotrophic lateral sclerosis/motor neuron diseasepanel. Sources: Radboud University Medical Center, Nijmegen,UKGTN,Illumina TruGenome Clinical Sequencing Services,Expert