Amyotrophic lateral sclerosis/motor neuron disease

Gene: GRN

Red List (low evidence)

GRN (granulin precursor)
EnsemblGeneIds (GRCh38): ENSG00000030582
EnsemblGeneIds (GRCh37): ENSG00000030582
OMIM: 138945, Gene2Phenotype
GRN is in 12 panels

1 review

Ellen McDonagh (Genomics England Curator)

Comment on list classification: May be a disease-modifying genes - see PMID: 24488689.
Created: 15 Jun 2016, 2:21 p.m.

History Filter Activity

19 Dec 2016, Gel status: 1

panel promoted to version 1

Alice Gardham (Genomics England)

Promoted to version 1 on 19th December 2016 following external review and internal curation

15 Jun 2016, Gel status: 1

Gene classified by Genomics England curator

Ellen McDonagh (Genomics England Curator)

This gene has been classified as Red List (Low Evidence).

18 Aug 2015, Gel status: 0

Set Mode of Inheritance

Ellen McDonagh (Genomics England Curator)

Model of inheritance for gene GRN was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

18 Aug 2015, Gel status: 0

Added New Source

Ellen McDonagh (Genomics England Curator)

GRN was added to Amyotrophic lateral sclerosis/motor neuron diseasepanel. Source: Expert

18 Aug 2015, Gel status: 0

Added New Source

Ellen McDonagh (Genomics England Curator)

GRN was added to Amyotrophic lateral sclerosis/motor neuron diseasepanel. Sources: Expert