Cystic kidney disease
Gene: GLIS2
GLIS2 (GLIS family zinc finger 2)
EnsemblGeneIds (GRCh38): ENSG00000126603
EnsemblGeneIds (GRCh37): ENSG00000126603
OMIM: 608539, Gene2Phenotype
GLIS2 is in 11 panels
EnsemblGeneIds (GRCh38): ENSG00000126603
EnsemblGeneIds (GRCh37): ENSG00000126603
OMIM: 608539, Gene2Phenotype
GLIS2 is in 11 panels
2 reviews
Ellen Thomas (Genomics England Curator)
Comment on list classification: Insufficient evidence - await further research results.Created: 10 May 2016, 10:21 a.m.
Miranda Durkie (Genetics)
Nephronophthisis (AR)
Created: 22 Oct 2015, 11:19 a.m.
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Details
- Sources
-
- Expert Review Red
- Expert
- Phenotypes
-
- Ciliopathy genes associated with cystic kidney disease
- OMIM
- 608539
- Clinvar variants
- Variants in GLIS2
- Penetrance
- Complete
- Panels with this gene
-
- Renal ciliopathies
- Tubulointerstitial kidney disease
- Unexplained kidney failure in young people
- DDG2P
- Cystic kidney disease
- Fetal anomalies
- Skeletal dysplasia
- Thoracic dystrophies
- Primary ciliary disorders
- Rare multisystem ciliopathy disorders
- Childhood onset dystonia, chorea or related movement disorder
History Filter Activity
10 May 2016, Gel status: 1
Gene classified by Genomics England curator
Ellen Thomas (Genomics England Curator)This gene has been classified as Red List (Low Evidence).
10 May 2016, Gel status: 1
Gene classified by Genomics England curator
Ellen Thomas (Genomics England Curator)This gene has been classified as Red List (Low Evidence).
15 Jul 2015, Gel status: 0
Added New Source
Ellen McDonagh (Genomics England Curator)GLIS2 was added to Cystic kidney diseasepanel. Sources: Expert