Familial prostate cancer

Gene: PTEN

Red List (low evidence)

PTEN (phosphatase and tensin homolog)
EnsemblGeneIds (GRCh38): ENSG00000171862
EnsemblGeneIds (GRCh37): ENSG00000171862
OMIM: 601728, Gene2Phenotype
PTEN is in 56 panels

1 review

Ellen McDonagh (Genomics England Curator)

Sourced from COSMIC Census Gene List for germline prostate cancer.
Created: 26 Jan 2017, 3:51 p.m.

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Phenotypes
harmartoma, glioma, prostate, endometrial; Cowden syndrome, Bannayan-Riley-Ruvalcaba syndrome

Details

Mode of Inheritance
BIALLELIC, autosomal or pseudoautosomal
Sources
  • Other
Phenotypes
  • harmartoma, glioma, prostate, endometrial
  • Cowden syndrome, Bannayan-Riley-Ruvalcaba syndrome
OMIM
601728
Clinvar variants
Variants in PTEN
Penetrance
Complete
Panels with this gene

History Filter Activity

7 Mar 2017, Gel status: 0

panel promoted to version 1

Ellen McDonagh (Genomics England Curator)

07/03/2017 - revised and ready to promote to version 1.

26 Jan 2017, Gel status: 0

Added New Source

Ellen McDonagh (Genomics England Curator)

PTEN was added to Familial prostate cancerpanel. Sources: Other

26 Jan 2017, Gel status: 0

Created

Ellen McDonagh (Genomics England Curator)

PTEN was created by ellenmcdonagh