Sudden death in young people

Gene: FEV

No list

FEV (FEV, ETS transcription factor)
EnsemblGeneIds (GRCh38): ENSG00000163497
EnsemblGeneIds (GRCh37): ENSG00000163497
OMIM: 607150, Gene2Phenotype
FEV is in 1 panel

1 review

Rebecca Foulger (Genomics England curator)

Comment on list classification: Changed rating from red to grey: PMID:17597646 reports 3 polymorphisms in the FEV gene (two in exon 3, and one in the preceeding intron) but they are found in both SIDS cases and matched controls. They also report a heterozygous insertion mutation (IVS-191_190insA) upstream of the 5' exon 3 splice site in the FEV gene, which is unique to African-American SIDS cases. However PMID:19707175 report that this insertion polymorphism seems to be a common, likely nonpathogenic, variant in the African-American population.
Created: 6 Dec 2016, 4:33 p.m.


Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
  • Expert Review Removed
  • Literature
  • SIDS
  • Sudden infant death syndrome
Clinvar variants
Variants in FEV
Panels with this gene

History Filter Activity

26 Feb 2021, Gel status: 0

Added Tag

Arina Puzriakova (Genomics England Curator)

Tag curated_removed tag was added to gene: FEV.

19 Dec 2016, Gel status: 0

panel promoted to version 1

Ellen Thomas (Genomics England Curator)

This panel contains genes which aren't arrhythmic or metabolic causes of sudden death with normal post mortem.

6 Dec 2016, Gel status: 0

Gene classified by Genomics England curator

Rebecca Foulger (Genomics England curator)

This gene has been removed from the panel.

6 Dec 2016, Gel status: 0


Rebecca Foulger (Genomics England curator)

FEV was created by rfoulger

6 Dec 2016, Gel status: 0

Added New Source

Rebecca Foulger (Genomics England curator)

FEV was added to Sudden death in young peoplepanel. Sources: Literature