Sudden death in young people

Gene: PPA2

Green List (high evidence)

PPA2 (pyrophosphatase (inorganic) 2)
EnsemblGeneIds (GRCh38): ENSG00000138777
EnsemblGeneIds (GRCh37): ENSG00000138777
OMIM: 609988, Gene2Phenotype
PPA2 is in 12 panels

2 reviews

Ellen Thomas (Genomics England Curator)

Comment on list classification: Green on mitochondrial panel, but mutations in this gene could cause sudden death in young adults too, so to be kept separately on the sudden death panel.
Created: 19 Dec 2016, 4:38 p.m.

Richard Scott (Genomics England Curator)

Green List (high evidence)

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Publications

History Filter Activity

19 Dec 2016, Gel status: 4

panel promoted to version 1

Ellen Thomas (Genomics England Curator)

This panel contains genes which aren't arrhythmic or metabolic causes of sudden death with normal post mortem.

19 Dec 2016, Gel status: 4

Gene classified by Genomics England curator

Ellen Thomas (Genomics England Curator)

This gene has been classified as Green List (High Evidence).

29 Nov 2016, Gel status: 0

Added New Source

Rebecca Foulger (Genomics England curator)

PPA2 was added to Sudden death in young peoplepanel. Source: Literature

7 Nov 2016, Gel status: 0

Created

Richard Scott (Genomics England Curator)

PPA2 was created by richardhywel

7 Nov 2016, Gel status: 0

Added New Source

Richard Scott (Genomics England Curator)

PPA2 was added to Sudden death in young peoplepanel. Sources: Expert Review