1. Panels
  2. Ataxia and cerebellar anomalies - narrow panel
  3. PDYN
Genes in panel
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Ataxia and cerebellar anomalies - narrow panel

Gene: PDYN

Green List (high evidence)
PDYN (prodynorphin)
EnsemblGeneIds (GRCh38): ENSG00000101327
EnsemblGeneIds (GRCh37): ENSG00000101327
OMIM: 131340, Gene2Phenotype
PDYN is in 8 panels

1 review

Ida Ertmanska (Genomics England Curator)

Comment on phenotypes: OMIM phenotype updated.
Created: 25 Jun 2026, 7:06 p.m. | Last Modified: 25 Jun 2026, 7:06 p.m.
Panel Version: 9.7
Created: 25 Jun 2026, 7:06 p.m.
Last Modified: 25 Jun 2026, 7:06 p.m.
Panel version: 9.7

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Green
Phenotypes
  • Spinocerebellar ataxia 23, OMIM:610245
  • spinocerebellar ataxia type 23, MONDO:0012449
OMIM
131340
Clinvar variants
Variants in PDYN
Penetrance
None
Panels with this gene

History Filter Activity

25 Jun 2026, Gel status: 3

Set Phenotypes

Ida Ertmanska (Genomics England Curator)

Phenotypes for gene: PDYN were changed from Spinocerebellar ataxia 23 to Spinocerebellar ataxia 23, OMIM:610245; spinocerebellar ataxia type 23, MONDO:0012449

9 Jan 2019, Gel status: 4

Panel promoted to version 1.0

Louise Daugherty (Genomics England Curator)

Checked against super panel made up of the panel constituents. Ready to promote to version 1.

19 Dec 2018, Gel status: 4

Created, Added New Source, Set mode of inheritance, Set Phenotypes

Ellen McDonagh (Genomics England Curator)

gene: PDYN was added gene: PDYN was added to Ataxia and cerebellar anomalies - narrow panel. Sources: Expert Review Green Mode of inheritance for gene: PDYN was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Phenotypes for gene: PDYN were set to Spinocerebellar ataxia 23