1. Panels
  2. Inherited pancreatic cancer
  3. PRSS1
STRs in panel
Prev Next
Regions in panel
Prev Next

Inherited pancreatic cancer

Gene: PRSS1

Amber List (moderate evidence)
PRSS1 (protease, serine 1)
EnsemblGeneIds (GRCh38): ENSG00000204983
EnsemblGeneIds (GRCh37): ENSG00000204983
OMIM: 276000, Gene2Phenotype
PRSS1 is in 3 panels

3 reviews

Arina Puzriakova (Genomics England Curator)

Comment on phenotypes: This gene is also associated with Pancreatitis, hereditary (MIM#167800)
Created: 3 Mar 2021, 2:43 p.m. | Last Modified: 3 Mar 2021, 2:43 p.m.
Panel Version: 1.15
Created: 3 Mar 2021, 2:43 p.m.
Last Modified: 3 Mar 2021, 2:43 p.m.
Panel version: 1.15

Rachel Robinson (Leeds Genetics Laboratory)

I don't know

Publications

Created: 30 Jan 2019, 10:34 a.m.

Panel version: 0.3

Lara Hawkes (Genomics England)

Green List (high evidence)

Created: 30 Jan 2019, 10:34 a.m.

Panel version: 0.3

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • NHS GMS
  • Expert List
Phenotypes
  • Malignant pancreatic neoplasm, MONDO:0009831
OMIM
276000
Clinvar variants
Variants in PRSS1
Penetrance
None
Publications
Panels with this gene

History Filter Activity

3 Mar 2021, Gel status: 2

Set Phenotypes

Arina Puzriakova (Genomics England Curator)

Phenotypes for gene: PRSS1 were changed from to Malignant pancreatic neoplasm, MONDO:0009831

15 Oct 2019, Gel status: 2

Set publications

Rebecca Foulger (Genomics England curator)

Publications for gene: PRSS1 were set to

30 Jan 2019, Gel status: 2

Entity classified by Genomics England curator

Anna de Burca (Oxford University Hospitals NHS Foundation Trust)

Gene: prss1 has been classified as Amber List (Moderate Evidence).

30 Jan 2019, Gel status: 1

Set mode of inheritance

Ivone Leong (Genomics England Curator)

Mode of inheritance for gene: PRSS1 was changed from to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

30 Jan 2019, Gel status: 1

Created, Added New Source, Set mode of inheritance

Ivone Leong (Genomics England Curator)

gene: PRSS1 was added gene: PRSS1 was added to Inherited pancreatic cancer. Sources: Expert List,NHS GMS Mode of inheritance for gene: PRSS1 was set to