Inherited pancreatic cancerGene: PMS2
Comment on phenotypes: This gene is also associated with Colorectal cancer, hereditary nonpolyposis, type 4 (MIM# 614337); Mismatch repair cancer syndrome 4 (MIM# 619101)
Created: 3 Mar 2021, 2:40 p.m. | Last Modified: 3 Mar 2021, 2:40 p.m.
Panel Version: 1.14
Variants in this GENE are reported as part of current diagnostic practice
Tumor Suppressor. Biallelic phenotype.
Created: 5 Jul 2017, 12:19 p.m.
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Lynch Syndrome; CMMRD
Phenotypes for gene: PMS2 were changed from to Malignant pancreatic neoplasm, MONDO:0009831
Publications for gene: PMS2 were set to
Mode of inheritance for gene: PMS2 was changed from to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Gene: pms2 has been classified as Amber List (Moderate Evidence).
gene: PMS2 was added gene: PMS2 was added to Inherited pancreatic cancer. Sources: Expert List,NHS GMS Mode of inheritance for gene: PMS2 was set to