1. Panels
  2. Haematological malignancies cancer susceptibility
  3. RUNX1
STRs in panel
Prev Next
Regions in panel
Prev Next

Haematological malignancies cancer susceptibility

Gene: RUNX1

Green List (high evidence)
RUNX1 (runt related transcription factor 1)
EnsemblGeneIds (GRCh38): ENSG00000159216
EnsemblGeneIds (GRCh37): ENSG00000159216
OMIM: 151385, Gene2Phenotype
RUNX1 is in 7 panels

1 review

Clare Turnbull (Queen Mary University London)

Green List (high evidence)

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

Created: 26 Jul 2017, 11:15 a.m.

Panel version: 0.8

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Green
  • Curated sources
Phenotypes
  • Class: familial predisp to leukaemia (typ AD)
  • Quantitative and qualitative platelet disorders with propensity to myeloid malignancy, Familial platelet disorder with propensity to myeloid malignancy
  • AML, MDS
  • Thrombocytopenia
  • No other known cancer risks
OMIM
151385
Clinvar variants
Variants in RUNX1
Penetrance
Complete
Publications
Panels with this gene

History Filter Activity

7 Sep 2018, Gel status: 4

Panel promoted to version 1.0

Louise Daugherty (Genomics England Curator)

Ellen McDonagh: Comment on mode of inheritance

30 Jan 2018, Gel status: 4

Added New Source

Ellen McDonagh (Genomics England Curator)

Expert Review Green was added to RUNX1. Panel: Haematological malignancies pertinent cancer susceptibility

21 Jun 2017, Gel status: 0

Created

Ellen McDonagh (Genomics England Curator)

RUNX1 was created by ellenmcdonagh

21 Jun 2017, Gel status: 0

Added New Source

Ellen McDonagh (Genomics England Curator)

RUNX1 was added to Haematological malignanciespanel. Sources: Curated sources