Periodic fever syndromes
Gene: FGAEnsemblGeneIds (GRCh38): ENSG00000171560
EnsemblGeneIds (GRCh37): ENSG00000171560
OMIM: 134820, Gene2Phenotype
FGA is in 5 panels
1 review
Alice Gardham (Genomics England)
Comment on list classification: Mutations are 5' end of exon5Created: 2 Feb 2017, 1:29 p.m.
Many reported cases of FGA amyloidosis. Suggested gene in entry criteria for this gene panelCreated: 30 Jan 2017, 4:46 p.m.
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
Amyloidosis, familial visceral 105200
Publications
Details
- Mode of Inheritance
- MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
- Sources
-
- Expert Review Green
- Eligibility statement prior genetic testing
- Illumina TruGenome Clinical Sequencing Services
- Radboud University Medical Center, Nijmegen
- Phenotypes
-
- Amyloidosis, familial visceral, OMIM:105200
- OMIM
- 134820
- Clinvar variants
- Variants in FGA
- Penetrance
- Complete
- Publications
- Panels with this gene
History Filter Activity
Set Phenotypes
Arina Puzriakova (Genomics England Curator)Phenotypes for gene: FGA were changed from Amyloidosis, familial visceral 105200 to Amyloidosis, familial visceral, OMIM:105200
panel promoted to version 1
Rebecca Foulger (Genomics England curator)22nd February 2017: Promoted to V1. Panel was reviewed by Tracy Briggs and Alice Gardham. Panel was revised according to expert review and additional curation.
Set Mode of Inheritance
Rebecca Foulger (Genomics England curator)Mode of inheritance for FGA was changed to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Gene classified by Genomics England curator
Alice Gardham (Genomics England)This gene has been classified as Green List (High Evidence).
Gene classified by Genomics England curator
Alice Gardham (Genomics England)This gene has been classified as Green List (High Evidence).
Set Phenotypes
Alice Gardham (Genomics England)Phenotypes for FGA were set to Amyloidosis, familial visceral 105200
Set publications
Alice Gardham (Genomics England)Publications for FGA were set to 8097946
Gene classified by Genomics England curator
Alice Gardham (Genomics England)This gene has been classified as Green List (High Evidence).
Added New Source
Ellen McDonagh (Genomics England Curator)FGA was added to Periodic fever syndromes and amyloidosis panel. Sources: Eligibility statement prior genetic testing
Set Mode of Inheritance
Ellen McDonagh (Genomics England Curator)Model of inheritance for gene FGA was changed to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Added New Source
Ellen McDonagh (Genomics England Curator)FGA was added to Periodic fever syndromes and amyloidosis panel. Sources: Radboud University Medical Center, Nijmegen,Illumina TruGenome Clinical Sequencing Services,Eligibility Statements for GeL
Set Mode of Inheritance
Ellen McDonagh (Genomics England Curator)Model of inheritance for gene FGA was changed to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Added New Source
Ellen McDonagh (Genomics England Curator)FGA was added to Periodic fever syndromes and amyloidosis panel. Sources: Radboud University Medical Center, Nijmegen,Illumina TruGenome Clinical Sequencing Services,Eligibility Statements for GeL
Added New Source
Ellen McDonagh (Genomics England Curator)FGA was added to Periodic fever syndromes and amyloidosis panel. Sources: Radboud University Medical Center, Nijmegen,Illumina TruGenome Clinical Sequencing Services,Eligibility Statements for GeL