Endocrine neoplasia
Gene: MSH2
After NHS Genomic Medicine Service consideration, the rating of this gene has not been changed and remains Amber.Created: 2 Feb 2023, noon | Last Modified: 2 Feb 2023, noon
Panel Version: 2.2
This gene was proposed to be added to this panel with Green status by Soo-Mi Park (East Anglian Medical Genetics Service). No further evidence was provided.
This gene has been given an Amber rating and will reviewed by GMS before Green status is given.
Sources: Expert listCreated: 16 Feb 2021, 10:22 a.m.
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Tag Q2_21_rating was removed from gene: MSH2. Tag Q2_21_phenotype was removed from gene: MSH2. Tag Q2_21_expert_review was removed from gene: MSH2. Tag Q2_21_NHS_review was removed from gene: MSH2.
Tag Q2_21_expert_review tag was added to gene: MSH2.
Tag Q2_21_rating tag was added to gene: MSH2. Tag Q2_21_NHS_review tag was added to gene: MSH2.
Gene: msh2 has been classified as Amber List (Moderate Evidence).
gene: MSH2 was added gene: MSH2 was added to Endocrine neoplasms. Sources: Expert list Q2_21_phenotype tags were added to gene: MSH2. Mode of inheritance for gene: MSH2 was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Review for gene: MSH2 was set to AMBER