Inherited phaeochromocytoma and paraganglioma excluding NF1

Gene: NF1

Amber List (moderate evidence)

NF1 (neurofibromin 1)
EnsemblGeneIds (GRCh38): ENSG00000196712
EnsemblGeneIds (GRCh37): ENSG00000196712
OMIM: 613113, Gene2Phenotype
NF1 is in 31 panels

1 review

Ivone Leong (Genomics England Curator)

Green List (high evidence)

This gene was suggested to be added and given a Green rating by Ruth Casey (Cambridge University Hospital).

This gene is Green on the Inherited phaeochromocytoma and paraganglioma (Version 1.6). This gene should be reconsidered for inclusion in this panel by the GMS specialist group.
Sources: Expert list
Created: 16 Feb 2021, 11:06 a.m.

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

Phenotypes
NF1

Publications

History Filter Activity

23 Mar 2021, Gel status: 2

Added Tag, Added Tag

Ivone Leong (Genomics England Curator)

Tag Q2_21_rating tag was added to gene: NF1. Tag Q2_21_NHS_review tag was added to gene: NF1.

16 Feb 2021, Gel status: 2

Entity classified by Genomics England curator

Ivone Leong (Genomics England Curator)

Gene: nf1 has been classified as Amber List (Moderate Evidence).

16 Feb 2021, Gel status: 1

Created, Added New Source, Added Tag, Set mode of inheritance, Set publications, Set Phenotypes

Ivone Leong (Genomics England Curator)

gene: NF1 was added gene: NF1 was added to Inherited phaeochromocytoma and paraganglioma excluding NF1. Sources: Expert list Q2_21_phenotype tags were added to gene: NF1. Mode of inheritance for gene: NF1 was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Publications for gene: NF1 were set to 22429592; 16735498 Phenotypes for gene: NF1 were set to NF1 Review for gene: NF1 was set to GREEN