1. Panels
  2. Proteinuric renal disease
  3. TTC21B
STRs in panel
Prev Next
Regions in panel
Prev Next

Proteinuric renal disease

Gene: TTC21B

Red List (low evidence)
TTC21B (tetratricopeptide repeat domain 21B)
EnsemblGeneIds (GRCh38): ENSG00000123607
EnsemblGeneIds (GRCh37): ENSG00000123607
OMIM: 612014, Gene2Phenotype
TTC21B is in 19 panels

1 review

Eleanor Williams (Genomics England Curator)

I don't know

This gene was part of an initial gene list collated by Elizabeth Watson, North Bristol NHS Trust, February 2019 on behalf of the GMS Renal Specialist Test Group. Gene Symbol submitted: TTC21B; Suggested initial gene rating: amber; Evidence for inclusion: PMID: 26940125; PMID: 24876116 ; Other comments: Multiple reports in the literature of gene associated with nephronophthisis. Unclear of association with proteinuric renal disease
Created: 4 Feb 2019, 10:41 a.m.

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Phenotypes
Nephronophthisis 12 # 613820

Publications

Variants in this GENE are reported as part of current diagnostic practice

Created: 4 Feb 2019, 10:41 a.m.

Panel version: 1.16

History Filter Activity

23 Jun 2019, Gel status: 1

Set Phenotypes

Eleanor Williams (Genomics England Curator)

Phenotypes for gene: TTC21B were changed from to Nephronophthisis 12 # 613820

23 Jun 2019, Gel status: 1

Set publications

Eleanor Williams (Genomics England Curator)

Publications for gene: TTC21B were set to

4 Feb 2019, Gel status: 1

Created, Added New Source, Set mode of inheritance

Eleanor Williams (Genomics England Curator)

gene: TTC21B was added gene: TTC21B was added to Proteinuric renal disease. Sources: NHS GMS Mode of inheritance for gene: TTC21B was set to