Proteinuric renal disease

Gene: DHFR

Red List (low evidence)

DHFR (dihydrofolate reductase)
EnsemblGeneIds (GRCh38): ENSG00000228716
EnsemblGeneIds (GRCh37): ENSG00000228716
OMIM: 126060, Gene2Phenotype
DHFR is in 14 panels

2 reviews

Eleanor Williams (Genomics England Curator)

Red List (low evidence)

After checking with Elizabeth Watson, it was concluded that this gene was rating initially green in error. There is no evidence to support its inclusion on this panel.
Created: 26 Mar 2019, 3:25 p.m.
This gene was part of an initial gene list collated by Elizabeth Watson, North Bristol NHS Trust, February 2019 on behalf of the GMS Renal Specialist Test Group. Gene Symbol submitted: DHFR; Suggested initial gene rating: green; Evidence for inclusion: none provided; Other comments: Unaware of phenotype association with this gene
Created: 4 Feb 2019, 10:41 a.m.

Maggie Williams (North Bristol NHS Trust)

Red List (low evidence)

phenotype does not fit
Created: 19 Oct 2015, 1:24 p.m.

History Filter Activity

4 Feb 2019, Gel status: 1

Added New Source

Eleanor Williams (Genomics England Curator)

Source NHS GMS was added to DHFR.

27 May 2016, Gel status: 1

Gene classified by Genomics England curator

Ellen Thomas (Genomics England Curator)

This gene has been classified as Red List (Low Evidence).

28 Aug 2015, Gel status: 1

Added New Source

Ellen McDonagh (Genomics England Curator)

DHFR was added to Proteinuric renal diseasepanel. Sources: Radboud University Medical Center, Nijmegen