Mitochondrial disorders
Gene: DARS2
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Variants in this GENE are reported as part of current diagnostic practice
Comment on mode of inheritance: Confirmed on G2P and OMIM.Created: 10 Feb 2016, 12:03 p.m.
Comment on list classification: Both reveiwers agree this gene should be promoted from red to green.Created: 10 Feb 2016, 12:02 p.m.
Victorian Clinical Genetics Services was added to DARS2. Panel: Mitochondrial disorders
This gene has been classified as Green List (High Evidence).
Phenotypes for DARS2 were set to Multiple respiratory chain complex deficiencies (disorders of protein synthesis); Leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation, 611105
Mode of inheritance for DARS2 was changed to BIALLELIC, autosomal or pseudoautosomal
This gene has been classified as Green List (High Evidence).
DARS2 was added to All recognised syndromes and those with suggestive featurespanel. Sources: Expert,Expert list,Radboud University Medical Center, Nijmegen
DARS2 was added to All recognised syndromes and those with suggestive featurespanel. Sources: Expert,Expert list,Radboud University Medical Center, Nijmegen
DARS2 was added to All recognised syndromes and those with suggestive featurespanel. Sources: Expert,Expert list,Radboud University Medical Center, Nijmegen