Embryonal tumour of possible germline origin
Gene: TRIM37EnsemblGeneIds (GRCh38): ENSG00000108395
EnsemblGeneIds (GRCh37): ENSG00000108395
OMIM: 605073, Gene2Phenotype
TRIM37 is in 14 panels
1 review
Achchuthan Shanmugasundram (Genomics England Curator)
TRIM37 has been added to the panel for the clinical indication 'R456 Embryonal tumour of possible germline origin' with a green rating as agreed with the NHS Genomic Medicine Service.Created: 26 Jan 2026, 6:10 p.m. | Last Modified: 26 Jan 2026, 6:10 p.m.
Panel Version: 0.7
Comment on phenotypes: This gene has been associated with relevant phenotypes in OMIM (MIM #253250) and the OMIM record was last accessed on 30 December 2025.Created: 30 Dec 2025, 11:14 a.m. | Last Modified: 30 Dec 2025, 11:14 a.m.
Panel Version: 0.2
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
mulibrey nanism, MONDO:0009664; Mulibrey nanism, OMIM:253250
Details
- Mode of Inheritance
- BIALLELIC, autosomal or pseudoautosomal
- Sources
-
- Expert Review Green
- NHS GMS
- Phenotypes
-
- mulibrey nanism, MONDO:0009664
- Mulibrey nanism, OMIM:253250
- OMIM
- 605073
- Clinvar variants
- Variants in TRIM37
- Penetrance
- None
- Panels with this gene
-
- Fetal anomalies
- Childhood solid tumours cancer susceptibility
- Childhood solid tumours
- Clefting
- Monogenic short stature
- Childhood onset dystonia, chorea or related movement disorder
- Peroxisomal disorders
- Osteogenesis imperfecta
- Intellectual disability
- Likely inborn error of metabolism
- Embryonal tumour of possible germline origin
- IUGR and IGF abnormalities
- Undiagnosed metabolic disorders
- DDG2P
History Filter Activity
Created, Added New Source, Set mode of inheritance, Set Phenotypes
Achchuthan Shanmugasundram (Genomics England Curator)gene: TRIM37 was added gene: TRIM37 was added to Embryonal tumour of possible germline origin. Sources: NHS GMS,Expert Review Green Mode of inheritance for gene: TRIM37 was set to BIALLELIC, autosomal or pseudoautosomal Phenotypes for gene: TRIM37 were set to mulibrey nanism, MONDO:0009664; Mulibrey nanism, OMIM:253250