Genodermatoses with malignancies

Gene: SUFU

Green List (high evidence)

SUFU (SUFU negative regulator of hedgehog signaling)
EnsemblGeneIds (GRCh38): ENSG00000107882
EnsemblGeneIds (GRCh37): ENSG00000107882
OMIM: 607035, Gene2Phenotype
SUFU is in 18 panels

1 review

Ellen Thomas (Genomics England Curator)

Comment on list classification: At least 3 reported families with Gorlin phenotype and SUFU mutations.
Created: 15 Feb 2016, 12:06 p.m.

Details

History Filter Activity

15 Feb 2016, Gel status: 4

Gene classified by Genomics England curator

Ellen Thomas (Genomics England Curator)

This gene has been classified as Green List (High Evidence).

15 Feb 2016, Gel status: 4

Gene classified by Genomics England curator

Ellen Thomas (Genomics England Curator)

This gene has been classified as Green List (High Evidence).

15 Feb 2016, Gel status: 2

Set publications

Ellen Thomas (Genomics England Curator)

Publications for SUFU were set to PMID: 25403219

27 Aug 2015, Gel status: 2

Set Mode of Inheritance

Ellen McDonagh (Genomics England Curator)

Model of inheritance for gene SUFU was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

27 Aug 2015, Gel status: 2

Added New Source

Ellen McDonagh (Genomics England Curator)

SUFU was added to Genodermatoses with malignanciespanel. Source: Radboud University Medical Center, Nijmegen

27 Aug 2015, Gel status: 1

Added New Source

Ellen McDonagh (Genomics England Curator)

SUFU was added to Genodermatoses with malignanciespanel. Sources: Illumina TruGenome Clinical Sequencing Services,Radboud University Medical Center, Nijmegen