Sarcoma cancer susceptibility
Gene: T

T (T brachyury transcription factor)
EnsemblGeneIds (GRCh38): ENSG00000164458
EnsemblGeneIds (GRCh37): ENSG00000164458
OMIM: 601397, Gene2Phenotype
T is in 6 panels

2 reviews

Louise Daugherty (Genomics England Curator)

Added new-gene-name tag, new approved HGNC gene symbol is TBXT
Created: 25 May 2018, 8:47 a.m.

Created: 25 May 2018, 8:47 a.m.

Panel version: 0.34

Ellen McDonagh (Genomics England Curator)

This gene was reviewed by Lara Hawkes (Cancer Clinical Team, Genomics England) and agrees this should be included on this panel.
Created: 20 Aug 2018, 1:30 p.m.

Gene and evidence provided by Adrienne Flanagan, UCL.
Created: 14 May 2018, 4:01 p.m.

Created: 14 May 2018, 4:01 p.m.

Panel version: 0.35

Details

Mode of Inheritance

MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

Sources

Expert Review Green
Expert list

Phenotypes

Chordoma (disease), MONDO:0008978

Tags

new-gene-name cnv

OMIM

601397

Clinvar variants

Variants in T

Penetrance

None

Publications

Panels with this gene

History Filter Activity

22 Jan 2024, Gel status: 3

Set publications

Arina Puzriakova (Genomics England Curator)

Publications for gene: T were set to 19801981; 23064415

22 Jan 2024, Gel status: 3

Set Phenotypes

Arina Puzriakova (Genomics England Curator)

Phenotypes for gene: T were changed from Familial Chordoma; Chordoma to Chordoma (disease), MONDO:0008978

4 Nov 2021, Gel status: 3

Removed Tag, Added Tag

Arina Puzriakova (Genomics England Curator)

Tag cnvs was removed from gene: T. Tag cnv tag was added to gene: T.

7 Sep 2018, Gel status: 3

Panel promoted to version 1.0

Louise Daugherty (Genomics England Curator)

Ellen McDonagh: Gene and evidence provided by

14 May 2018, Gel status: 3