Gene therapy clinical trials

Gene: CNGB3

Green List (high evidence)

CNGB3 (cyclic nucleotide gated channel beta 3)
EnsemblGeneIds (GRCh38): ENSG00000170289
EnsemblGeneIds (GRCh37): ENSG00000170289
OMIM: 605080, Gene2Phenotype
CNGB3 is in 5 panels

1 review

Ellen McDonagh (Genomics England Curator)

Green List (high evidence)

Biological: AAV - CNGB3. Trials https://ClinicalTrials.gov/show/NCT03001310 and https://ClinicalTrials.gov/show/NCT03278873
Created: 2 May 2018, 3:12 p.m.

Phenotypes
Achromatopsia

Details

Sources
  • Expert Review Green
  • ClinicalTrials.gov
Phenotypes
  • Achromatopsia
OMIM
605080
Clinvar variants
Variants in CNGB3
Penetrance
None
Panels with this gene

History Filter Activity

12 May 2018, Gel status: 4

Set penetrance

Ellen McDonagh (Genomics England Curator)

Phenotypes for gene CNGB3 were set to Achromatopsia

2 May 2018, Gel status: 4

Added New Source

Ellen McDonagh (Genomics England Curator)

CNGB3 was added to Gene therapy clinical trials panel. Sources: ClinicalTrials.gov,Expert Review Green

2 May 2018, Gel status: 4

Created

Ellen McDonagh (Genomics England Curator)

CNGB3 was created by Ellen McDonagh