Gene therapy clinical trials

Gene: CYBB

Green List (high evidence)

CYBB (cytochrome b-245 beta chain)
EnsemblGeneIds (GRCh38): ENSG00000165168
EnsemblGeneIds (GRCh37): ENSG00000165168
OMIM: 300481, Gene2Phenotype
CYBB is in 7 panels

1 review

Ellen McDonagh (Genomics England Curator)

Green List (high evidence)

Genetic: pCCLchimGp91s lentiviral vector transduced CD34+ cells infusion - trial https://ClinicalTrials.gov/show/NCT01381003, Genetic: X vivo gene therapy - trial https://ClinicalTrials.gov/show/NCT01855685
Created: 12 May 2018, 8:57 a.m.

Phenotypes
Granulomatous Disease, Chronic, X-linked

History Filter Activity

12 May 2018, Gel status: 4

Set penetrance

Ellen McDonagh (Genomics England Curator)

Phenotypes for gene CYBB were set to Granulomatous Disease, Chronic, X-linked

2 May 2018, Gel status: 4

Added New Source

Ellen McDonagh (Genomics England Curator)

CYBB was added to Gene therapy clinical trials panel. Sources: ClinicalTrials.gov,Expert Review Green

2 May 2018, Gel status: 4

Created

Ellen McDonagh (Genomics England Curator)

CYBB was created by Ellen McDonagh