Gene therapy clinical trials

Gene: F8

Green List (high evidence)

F8 (coagulation factor VIII)
EnsemblGeneIds (GRCh38): ENSG00000185010
EnsemblGeneIds (GRCh37): ENSG00000185010
OMIM: 300841, Gene2Phenotype
F8 is in 4 panels

1 review

Ellen McDonagh (Genomics England Curator)

Green List (high evidence)

Biological: AAV2/8-HLP-FVIII-V3 - https://ClinicalTrials.gov/show/NCT03001830, Genetic: BMN 270 - https://ClinicalTrials.gov/show/NCT02576795
Created: 12 May 2018, 8:57 a.m.

Phenotypes
Haemophilia A; Severe Haemophilia A

Details

Sources
  • Expert Review Green
  • ClinicalTrials.gov
Phenotypes
  • Haemophilia A
  • Severe Haemophilia A
OMIM
300841
Clinvar variants
Variants in F8
Penetrance
None
Panels with this gene

History Filter Activity

12 May 2018, Gel status: 4

Added New Source

Ellen McDonagh (Genomics England Curator)

F8 was added to Gene therapy clinical trials panel. Sources: ClinicalTrials.gov,Expert Review Green

12 May 2018, Gel status: 4

Created

Ellen McDonagh (Genomics England Curator)

F8 was created by Ellen McDonagh