This Panel is marked as Internal
Gene therapy clinical trials
Gene: WAS
WAS (Wiskott-Aldrich syndrome)
EnsemblGeneIds (GRCh38): ENSG00000015285
EnsemblGeneIds (GRCh37): ENSG00000015285
OMIM: 300392, Gene2Phenotype
WAS is in 11 panels
EnsemblGeneIds (GRCh38): ENSG00000015285
EnsemblGeneIds (GRCh37): ENSG00000015285
OMIM: 300392, Gene2Phenotype
WAS is in 11 panels
1 review
Ellen McDonagh (Genomics England Curator)
Genetic: Autologous CD34 positive cells transduced with a lentiviral vector containing human WAS gene - https://ClinicalTrials.gov/show/NCT01347242, Genetic: Autologous CD34+ cells transduced with WASP lentiviral vector - https://ClinicalTrials.gov/show/NCT02333760Created: 12 May 2018, 8:57 a.m.
Phenotypes
Wiskott Aldrich syndrome
Details
- Sources
-
- Expert Review Green
- ClinicalTrials.gov
- Phenotypes
-
- Wiskott Aldrich syndrome
- OMIM
- 300392
- Clinvar variants
- Variants in WAS
- Penetrance
- None
- Panels with this gene
-
- Infantile enterocolitis & monogenic inflammatory bowel disease
- Haematological malignancies for rare disease
- Cytopenia - NOT Fanconi anaemia
- Cytopenias and congenital anaemias
- Primary immunodeficiency or monogenic inflammatory bowel disease
- Bleeding and platelet disorders
- Haematological malignancies cancer susceptibility
- Inherited bleeding disorders
- Gastrointestinal epithelial barrier disorders
- COVID-19 research
- Wiskott-Aldrich syndrome
History Filter Activity
12 May 2018, Gel status: 4
Added New Source
Ellen McDonagh (Genomics England Curator)WAS was added to Gene therapy clinical trials panel. Sources: ClinicalTrials.gov,Expert Review Green
12 May 2018, Gel status: 4
Created
Ellen McDonagh (Genomics England Curator)WAS was created by Ellen McDonagh