Laterality disorders and isomerismGene: LZTFL1
Initial gene list and info collated by Ian Berry Leeds Genetics Laboratory November 2018 on behalf of the GMS Respiratory specialist test group. Gene Symbol submitted: LZTFL1; Suggested initial gene rating: Amber; Evidence for inclusion: BBS17 in OMIM; rare reports of dextrocardia; Evidence for exclusion: Laterality abnormalities seen in <2% of BBS patients (CRIBBS), disorder is syndromic and otherwise recognisable; polydactyly/delay more prominent early features.; Technical notes (e.g. non-coding/CNV mutations requiring coverage?): none given
Created: 5 Dec 2018, 12:52 p.m.
Source Expert Review Amber was added to LZTFL1. Rating Changed from Red List (low evidence) to Amber List (moderate evidence)
gene: LZTFL1 was added gene: LZTFL1 was added to Laterality disorders and isomerism. Sources: NHS GMS Mode of inheritance for gene: LZTFL1 was set to