Laterality disorders and isomerismGene: NME8
No further cases reported since 2015. Discussed with NHS GMS respiratory specialist group including Hannah Mitchison 18/01/19, decision made to downgrade to red.
Created: 18 Jan 2019, 9:48 p.m.
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Initial gene list and info collated by Ian Berry Leeds Genetics Laboratory November 2018 on behalf of the GMS Respiratory specialist test group. Gene Symbol submitted: NME8; Suggested initial gene rating: Green; Evidence for inclusion: OMIM PCD or Visceral heterotaxy gene; Evidence for exclusion: none given; Technical notes (e.g. non-coding/CNV mutations requiring coverage?): none given
Created: 5 Dec 2018, 12:52 p.m.
Mode of inheritance for gene: NME8 was changed from to BIALLELIC, autosomal or pseudoautosomal
Publications for gene: NME8 were set to
Gene: nme8 has been classified as Red List (Low Evidence).
Source Expert Review Green was added to NME8. Rating Changed from Red List (low evidence) to Green List (high evidence)
gene: NME8 was added gene: NME8 was added to Laterality disorders and isomerism. Sources: NHS GMS Mode of inheritance for gene: NME8 was set to