Thoracic aortic aneurysm and dissectionGene: MYLK2
Submitted on behalf of the GMS Cardiology specialist group. The group has agreed that this gene should be Red on this panel.
Created: 18 Nov 2019, 4:33 p.m. | Last Modified: 18 Nov 2019, 4:33 p.m.
Panel Version: 0.35
Could not find literature associating MYLK2 with aortopathy, MYLK is associated with aortopathy (PubMed 21055718).
Created: 2 Oct 2019, 3:06 p.m. | Last Modified: 2 Oct 2019, 3:06 p.m.
Panel Version: 0.32
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Cardiomyopathy, hypertrophic, 1, digenic 192600
This gene was part of an initial gene list collated by Matthew Edwards Royal Brompton Hospital sent 16th Jan 2019 on behalf of the London South GLH for review by the GMS Cardiology Specialist Group. Only gene symbol from the Royal Brompton gene panel was provided - suggested initial gene rating and evidence for inclusion not provided with the list.
Created: 20 Feb 2019, 2:17 p.m.
gene: MYLK2 was added gene: MYLK2 was added to GMS FTAAD placeholder panel. Sources: London South GLH,Expert Review Red Mode of inheritance for gene: MYLK2 was set to