BRIDGE_SPEED_NEURO_v2.0_20160416
Gene: SNCA

SNCA (synuclein alpha)
EnsemblGeneIds (GRCh38): ENSG00000145335
EnsemblGeneIds (GRCh37): ENSG00000145335
OMIM: 163890, Gene2Phenotype
SNCA is in 5 panels

1 review

BRIDGE consortium (NIHRBR-RD)

Green List (high evidence)

manju_list; neuro_20160418_strict; NA
Created: 7 Feb 2017, 4:57 p.m.

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

Phenotypes
Parkinson disease 4, 605543; Dementia, Lewy body, 127750; Parkinson disease 1, 168601;

Variants in this GENE are reported as part of current diagnostic practice

Created: 7 Feb 2017, 4:57 p.m.

Panel version: 0.2

Details

Mode of Inheritance

MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

Sources

BRIDGE

Phenotypes

Parkinson disease 4, 605543
Dementia, Lewy body, 127750
Parkinson disease 1, 168601

OMIM

163890

Clinvar variants

Variants in SNCA

Penetrance

Complete

Panels with this gene

History Filter Activity

7 Feb 2017, Gel status: 0

Added New Source

Ellen McDonagh (Genomics England Curator)

SNCA was added to BRIDGE_SPEED_NEURO_v2.0_20160416panel. Sources: BRIDGE

7 Feb 2017, Gel status: 0

Created