IUGR and IGF abnormalities

Gene: CDT1

Green List (high evidence)

CDT1 (chromatin licensing and DNA replication factor 1)
EnsemblGeneIds (GRCh38): ENSG00000167513
EnsemblGeneIds (GRCh37): ENSG00000167513
OMIM: 605525, Gene2Phenotype
CDT1 is in 8 panels

3 reviews

Peter Clayton (University of Manchester)

Green List (high evidence)

Philip Murray (University of Manchester)

Green List (high evidence)

emma baple (Genomics England Curator)

Comment on phenotypes: Meier Gorlin
Created: 3 Apr 2016, 8:24 p.m.

Details

Mode of Inheritance
BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
Phenotypes
  • micrognathia, microtia, patellar hypoplasia/aplasia, mammary hypoplasia
OMIM
605525
Clinvar variants
Variants in CDT1
Penetrance
Complete
Publications
Panels with this gene

History Filter Activity

3 Apr 2016, Gel status: 4

Gene classified by Genomics England curator

emma baple (Genomics England Curator)

This gene has been classified as Green List (High Evidence).

3 Apr 2016, Gel status: 4

Set Phenotypes

emma baple (Genomics England Curator)

Phenotypes for CDT1 were set to micrognathia, microtia, patellar hypoplasia/aplasia, mammary hypoplasia

3 Apr 2016, Gel status: 4

Gene classified by Genomics England curator

emma baple (Genomics England Curator)

This gene has been classified as Green List (High Evidence).

23 Oct 2015, Gel status: 0

Added New Source

Philip Murray (University of Manchester)

CDT1 was added to IUGR and IGF abnormalitiespanel. Sources: Literature

23 Oct 2015, Gel status: 0

Created

Philip Murray (University of Manchester)

CDT1 was created by PhilMurray