IUGR and IGF abnormalities

Gene: IGF2

Red List (low evidence)

IGF2 (insulin like growth factor 2)
EnsemblGeneIds (GRCh38): ENSG00000167244
EnsemblGeneIds (GRCh37): ENSG00000167244
OMIM: 147470, Gene2Phenotype
IGF2 is in 8 panels

5 reviews

Mehul Dattani (UCL Institute of Child Health)

Green List (high evidence)

Philip Murray (University of Manchester)

Green List (high evidence)

Peter Clayton (University of Manchester)

Green List (high evidence)

Ellen McDonagh (Genomics England Curator)

Added watchlist tag.
8 Dec 2016, 10:35 a.m.

Richard Scott (Genomics England Curator)

Comment on list classification: Only one reported family with point mutation reported - insufficient for panel at this stage.
2 May 2016, 9:22 p.m.

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, maternally imprinted (paternal allele expressed)
Sources
  • Expert Review Red
Phenotypes
  • Pre- and post-natal growth failure
  • Silver-Russell phenptype
  • IUGR
Tags
watchlist
OMIM
147470
Clinvar variants
Variants in IGF2
Penetrance
Complete
Publications
Panels with this gene

History Filter Activity

2 May 2016, Gel status: 1

Gene classified by Genomics England curator

Richard Scott (Genomics England Curator)

This gene has been classified as Red List (Low Evidence).

2 May 2016, Gel status: 1

Gene classified by Genomics England curator

Richard Scott (Genomics England Curator)

This gene has been classified as Red List (Low Evidence).

26 Oct 2015, Gel status: 0

Added New Source

Mehul Dattani (UCL Institute of Child Health)

IGF2 was added to IUGR and IGF abnormalitiespanel. Source: Expert Review

22 Oct 2015, Gel status: 0

Added New Source

Peter Clayton (University of Manchester)

IGF2 was added to IUGR and IGF abnormalitiespanel. Sources: Literature

22 Oct 2015, Gel status: 0

Created

Peter Clayton (University of Manchester)

IGF2 was created by peter.clayton