IUGR and IGF abnormalities

Gene: GPR161

Red List (low evidence)

GPR161 (G protein-coupled receptor 161)
EnsemblGeneIds (GRCh38): ENSG00000143147
EnsemblGeneIds (GRCh37): ENSG00000143147
OMIM: 612250, Gene2Phenotype
GPR161 is in 3 panels

2 reviews

Peter Clayton (University of Manchester)

Red List (low evidence)

Mehul Dattani (UCL Institute of Child Health)

Red List (low evidence)

Details

Mode of Inheritance
BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Red
Phenotypes
  • Short stature with hypopituitarism, intellectual disability, sparse or absent hair in the frontal area, hypotelorism, broad nasal root, thick alae nasi, nail hypoplasia, short fifth finger, 2-3 toe syndactyl. MRI showed hypoplastic pituitary gland, empty sella, ectopic neurohypophysis, and interrupted pituitary stalk
OMIM
612250
Clinvar variants
Variants in GPR161
Penetrance
Complete
Publications
Panels with this gene

History Filter Activity

25 Apr 2016, Gel status: 1

Gene classified by Genomics England curator

emma baple (Genomics England Curator)

This gene has been classified as Red List (Low Evidence).

25 Apr 2016, Gel status: 1

Gene classified by Genomics England curator

emma baple (Genomics England Curator)

This gene has been classified as Red List (Low Evidence).

25 Oct 2015, Gel status: 0

Added New Source

Mehul Dattani (UCL Institute of Child Health)

GPR161 was added to IUGR and IGF abnormalitiespanel. Sources: Expert Review,Literature

25 Oct 2015, Gel status: 0

Created

Mehul Dattani (UCL Institute of Child Health)

GPR161 was created by mdattani