IUGR and IGF abnormalities

Gene: CUL7

Green List (high evidence)

CUL7 (cullin 7)
EnsemblGeneIds (GRCh38): ENSG00000044090
EnsemblGeneIds (GRCh37): ENSG00000044090
OMIM: 609577, Gene2Phenotype
CUL7 is in 8 panels

4 reviews

Mehul Dattani (UCL Institute of Child Health)

Green List (high evidence)

Philip Murray (University of Manchester)

Green List (high evidence)

Peter Clayton (University of Manchester)

Green List (high evidence)

Rebecca Foulger (Genomics England curator)

Comment on phenotypes: Updated phenotype field to include current OMIM disorder and ID (MIM:273750)
17 Aug 2017, 9:36 a.m.

Details

Mode of Inheritance
BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Emory Genetics Laboratory
Phenotypes
  • 3-M syndrome 1, 273750
OMIM
609577
Clinvar variants
Variants in CUL7
Penetrance
Complete
Panels with this gene

History Filter Activity

17 Aug 2017, Gel status: 4

Set Phenotypes

Rebecca Foulger (Genomics England curator)

Phenotypes for CUL7 were set to 3-M syndrome 1, 273750

3 Apr 2016, Gel status: 4

Gene classified by Genomics England curator

emma baple (Genomics England Curator)

This gene has been classified as Green List (High Evidence).

3 Apr 2016, Gel status: 4

Set Phenotypes

emma baple (Genomics England Curator)

Phenotypes for CUL7 were set to 3M syndrome

3 Apr 2016, Gel status: 4

Set Mode of Inheritance

emma baple (Genomics England Curator)

Mode of inheritance for CUL7 was changed to BIALLELIC, autosomal or pseudoautosomal

3 Apr 2016, Gel status: 4

Gene classified by Genomics England curator

emma baple (Genomics England Curator)

This gene has been classified as Green List (High Evidence).

28 Apr 2015, Gel status: 1

Added New Source

GEL ()

CUL7 was added to IUGR and IGF abnormalitiespanel. Sources: Emory Genetics Laboratory