IUGR and IGF abnormalities
Gene: IGF2
IGF2 (insulin like growth factor 2)
EnsemblGeneIds (GRCh38): ENSG00000167244
EnsemblGeneIds (GRCh37): ENSG00000167244
OMIM: 147470, Gene2Phenotype
IGF2 is in 8 panels
EnsemblGeneIds (GRCh38): ENSG00000167244
EnsemblGeneIds (GRCh37): ENSG00000167244
OMIM: 147470, Gene2Phenotype
IGF2 is in 8 panels
5 reviews
Mehul Dattani (UCL Institute of Child Health)
Philip Murray (University of Manchester)
Peter Clayton (University of Manchester)
Ellen McDonagh (Genomics England Curator)
Added watchlist tag.Created: 8 Dec 2016, 10:35 a.m.
Richard Scott (Genomics England Curator)
Comment on list classification: Only one reported family with point mutation reported - insufficient for panel at this stage.Created: 2 May 2016, 9:22 p.m.
Details
- Mode of Inheritance
- MONOALLELIC, autosomal or pseudoautosomal, maternally imprinted (paternal allele expressed)
- Sources
-
- Expert Review Red
- Phenotypes
-
- Pre- and post-natal growth failure
- Silver-Russell phenptype
- IUGR
- Tags
- OMIM
- 147470
- Clinvar variants
- Variants in IGF2
- Penetrance
- Complete
- Publications
- Panels with this gene
History Filter Activity
2 May 2016, Gel status: 1
Gene classified by Genomics England curator
Richard Scott (Genomics England Curator)This gene has been classified as Red List (Low Evidence).
2 May 2016, Gel status: 1
Gene classified by Genomics England curator
Richard Scott (Genomics England Curator)This gene has been classified as Red List (Low Evidence).
26 Oct 2015, Gel status: 0
Added New Source
Mehul Dattani (UCL Institute of Child Health)IGF2 was added to IUGR and IGF abnormalitiespanel. Source: Expert Review
22 Oct 2015, Gel status: 0
Added New Source
Peter Clayton (University of Manchester)IGF2 was added to IUGR and IGF abnormalitiespanel. Sources: Literature
22 Oct 2015, Gel status: 0
Created
Peter Clayton (University of Manchester)IGF2 was created by peter.clayton