Inherited ovarian cancer (without breast cancer)
Gene: RAD51DAs discussed in the GMS Inherited Cancer Specialist Test Group webex call 31st Jan 2019: The Specialist Test Group agreed that there is enough evidence to rate this gene green.Created: 31 Jul 2019, 12:24 p.m. | Last Modified: 31 Jul 2019, 12:24 p.m.
Panel Version: 1.9
Publications
Variants in this GENE are reported as part of current diagnostic practice
relative risk ~6Created: 29 Aug 2017, 1:18 p.m.
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Variants in this GENE are reported as part of current diagnostic practice
Comment on list classification: This gene is reported as part of pertinent germline findings for the Cancer Programme for patients with ovarian cancer.Created: 30 May 2017, 11:28 a.m.
Phenotypes for gene: RAD51D were changed from {Breast-ovarian cancer, familial, susceptibility to, 4}, 614291; Breast and Ovarian Cancer; Breast and Ovarian Cancer Susceptibility to {Breast-ovarian cancer, familial, susceptibility to, 4}, OMIM:614291; Breast-ovarian cancer, familial, susceptibility to, 4, MONDO:0013669
Publications for gene: RAD51D were set to
Source Expert List was added to RAD51D. Source NHS GMS was added to RAD51D. Rating Changed from Green List (high evidence) to Green List (high evidence)
31/07/2017: Promoted panel to version 1, after checking against the original list sent by Clare Turnbull for this panel.
This gene has been classified as Green List (High Evidence).
This gene has been classified as Green List (High Evidence).
RAD51D was created by ellenmcdonagh
RAD51D was added to Familial ovarian cancerpanel. Sources: Radboud University Medical Center, Nijmegen,Emory Genetics Laboratory,Illumina TruGenome Clinical Sequencing Services,Expert Review Green