Inherited ovarian cancer (without breast cancer)

Gene: ATM

Red List (low evidence)

ATM (ATM serine/threonine kinase)
EnsemblGeneIds (GRCh38): ENSG00000149311
EnsemblGeneIds (GRCh37): ENSG00000149311
OMIM: 607585, Gene2Phenotype
ATM is in 30 panels

0 reviews

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Emory Genetics Laboratory
  • Expert Review Red
  • Radboud University Medical Center, Nijmegen
Phenotypes
  • Ataxia-telangiectasia, 208900
  • Lymphoma, B-cell non-Hodgkin, somatic
  • {Breast cancer, susceptibility to}, 114480
  • Lymphoma, mantle cell
  • T-cell prolymphocytic leukemia, somatic
  • Breast and Ovarian Cancer
OMIM
607585
Clinvar variants
Variants in ATM
Penetrance
Complete
Panels with this gene

History Filter Activity

31 Jul 2017, Gel status: 1

panel promoted to version 1

Ellen McDonagh (Genomics England Curator)

31/07/2017: Promoted panel to version 1, after checking against the original list sent by Clare Turnbull for this panel.

26 May 2017, Gel status: 1

Added New Source

Ellen McDonagh (Genomics England Curator)

ATM was added to Familial ovarian cancerpanel. Sources: Radboud University Medical Center, Nijmegen,Emory Genetics Laboratory,Expert Review Red

26 May 2017, Gel status: 0

Created

Ellen McDonagh (Genomics England Curator)

ATM was created by ellenmcdonagh