Inherited ovarian cancer (without breast cancer)
Gene: STK11
STK11 (serine/threonine kinase 11)
EnsemblGeneIds (GRCh38): ENSG00000118046
EnsemblGeneIds (GRCh37): ENSG00000118046
OMIM: 602216, Gene2Phenotype
STK11 is in 14 panels
EnsemblGeneIds (GRCh38): ENSG00000118046
EnsemblGeneIds (GRCh37): ENSG00000118046
OMIM: 602216, Gene2Phenotype
STK11 is in 14 panels
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Details
- Mode of Inheritance
- MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
- Sources
-
- Emory Genetics Laboratory
- Phenotypes
-
- High Risk Breast Cancer
- Breast and Ovarian Cancer
- OMIM
- 602216
- Clinvar variants
- Variants in STK11
- Penetrance
- Complete
- Publications
-
- PMID: 11113065
- Panels with this gene
-
- Inherited ovarian cancer (without breast cancer)
- Childhood solid tumours cancer susceptibility
- Colorectal cancer pertinent cancer susceptibility
- Adult solid tumours for rare disease
- Familial breast cancer
- Palmoplantar keratodermas
- Adult solid tumours cancer susceptibility
- GI tract tumours
- Inherited pancreatic cancer
- Inherited polyposis and early onset colorectal cancer - germline testing
- Peutz Jeghers Syndrome
- Pigmentary skin disorders
- Childhood solid tumours
- Multiple monogenic benign skin tumours
History Filter Activity
31 Jul 2017, Gel status: 1
panel promoted to version 1
Ellen McDonagh (Genomics England Curator)31/07/2017: Promoted panel to version 1, after checking against the original list sent by Clare Turnbull for this panel.
26 May 2017, Gel status: 1
Added New Source
Ellen McDonagh (Genomics England Curator)STK11 was added to Familial ovarian cancerpanel. Sources: Emory Genetics Laboratory
26 May 2017, Gel status: 0
Created
Ellen McDonagh (Genomics England Curator)STK11 was created by ellenmcdonagh