Cytopenias and congenital anaemiasGene: ITGB3
None of the phenotypes are consistent with the inclusion criteria. Glanzmann thrombasthenia is an inherited (AR) bleeding disorder (green on this panel), where as NAIT is a transient albeit potentially serious condition in a neonate which causes thrombocytopaenia owing to genetic differences between parents of a fetus (mother has antibodies to a platelet antigen, fetus has the antigen). Not appropriate for inclusion on this panel.
Created: 9 Mar 2017, 4:32 p.m.
Mode of inheritance
Other - please specify in evaluation comments
PL(A) platelet antigen neonatal alloimmune thrombocytopaenia; Glanzmann thrombasthenia, 273800
Promoted to V1 on 11 March 2017, after internal review and discussion with the clinical team.
ITGB3 was added to Cytopaenias and congenital anaemiaspanel. Source: Expert Review Red Model of inheritance for gene ITGB3 was set to Other - please specify in evaluation comments
ITGB3 was added to Cytopaenias and congenital anaemiaspanel. Sources: Radboud University Medical Center, Nijmegen
ITGB3 was created by LouiseD