Inherited non-medullary thyroid cancer
Gene: FOXE1Comment when marking as ready: Associated with phenotype in OMIM, not in G2P. At least one variant reported in two apparently unrelated cases, supportive animal cell line data also available (PMID: 25381600)Created: 31 Jul 2017, 12:34 p.m.
Comment on phenotypes: Biallelic variants associated with Bamforth-Lazarus syndrome 241850Created: 31 Jul 2017, 12:30 p.m.
SNP 60kb from FOXE1 has shown association with NMTC in GWAS studies but no causative role of FOXE1 been demonstrated as yet.Created: 13 Jun 2017, 2:06 p.m.
SNP 60kb from FOXE1 has shown association with NMTC in GWAS studies but no causative role of FOXE1 been demonstrated as yet.Created: 13 Jun 2017, 2:06 p.m.
GWAS suggest some association but not clear. No clinical utilityCreated: 9 Jun 2017, 9:10 a.m.
All genes have been reviewed and the reviews evaluated. 07.08.2017
This gene has been classified as Amber List (Moderate Evidence).
This gene has been classified as Amber List (Moderate Evidence).
Phenotypes for FOXE1 were set to {Thyroid cancer, nonmedullary, 4} 616534
FOXE1 was created by sleigh
FOXE1 was added to Inherited non-medullary thyroid cancerpanel. Sources: Radboud University Medical Center, Nijmegen