Inherited non-medullary thyroid cancer

Gene: BRAF

Red List (low evidence)

BRAF (B-Raf proto-oncogene, serine/threonine kinase)
EnsemblGeneIds (GRCh38): ENSG00000157764
EnsemblGeneIds (GRCh37): ENSG00000157764
OMIM: 164757, Gene2Phenotype
BRAF is in 20 panels

1 review

Sarah Leigh (Genomics England Curator)

Red List (low evidence)

Comment when marking as ready: Associated with phenotype in OMIM, not in G2P. At least one variant reported in two patients.
Created: 31 Jul 2017, 10:53 a.m.
Single variant identified in two members of one family (PMID 26530882).
Created: 31 Jul 2017, 10:50 a.m.

Mode of inheritance
Unknown

Phenotypes
Familial Non-medullary Thyroid Cancer

Publications

History Filter Activity

7 Aug 2017, Gel status: 1

panel promoted to version 1

Sarah Leigh (Genomics England Curator)

All genes have been reviewed and the reviews evaluated. 07.08.2017

31 Jul 2017, Gel status: 1

Gene classified by Genomics England curator

Sarah Leigh (Genomics England Curator)

This gene has been classified as Red List (Low Evidence).

21 Jun 2017, Gel status: 0

Created

Sarah Leigh (Genomics England Curator)

BRAF was created by sleigh

21 Jun 2017, Gel status: 0

Added New Source

Sarah Leigh (Genomics England Curator)

BRAF was added to Inherited non-medullary thyroid cancerpanel. Sources: Literature