Inherited non-medullary thyroid cancer
Gene: PTCSC1
PTCSC1 (papillary thyroid carcinoma susceptibility candidate 1 (non-protein coding))
OMIM: 617440, Gene2Phenotype
PTCSC1 is in 1 panel
OMIM: 617440, Gene2Phenotype
PTCSC1 is in 1 panel
3 reviews
Eleanor Williams (Genomics England Curator)
Ensembl identifiers not available for GRCh37 (release 82) or GRCh38 (release 90)Created: 8 Jul 2020, 2:22 p.m. | Last Modified: 8 Jul 2020, 2:22 p.m.
Panel Version: 1.4
Sarah Leigh (Genomics England Curator)
Comment when marking as ready: Down regulation of PTCSC1 in papillary thyroid carcinoma (PMID 19147577)Created: 7 Aug 2017, 12:37 p.m.
Emma Woodward (Manchester Centre for Genomic Medicine)
Insufficient evidence for clinical utilityCreated: 13 Jun 2017, 2:50 p.m.
Details
- Mode of Inheritance
- MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
- Sources
-
- Expert Review Red
- Literature
- Phenotypes
-
- papillary thyroid, susceptibility
- Tags
- OMIM
- 617440
- Clinvar variants
- Variants in PTCSC1
- Penetrance
- Complete
- Publications
- Panels with this gene
History Filter Activity
8 Jul 2020, Gel status: 1
Added Tag
Eleanor Williams (Genomics England Curator)Tag ensembl_ids_known_missing tag was added to gene: PTCSC1.
7 Aug 2017, Gel status: 1
panel promoted to version 1
Sarah Leigh (Genomics England Curator)All genes have been reviewed and the reviews evaluated. 07.08.2017
7 Aug 2017, Gel status: 1
Gene classified by Genomics England curator
Sarah Leigh (Genomics England Curator)This gene has been classified as Red List (Low Evidence).
18 May 2017, Gel status: 0
Created
Sarah Leigh (Genomics England Curator)PTCSC1 was created by sleigh
18 May 2017, Gel status: 0
Added New Source
Sarah Leigh (Genomics England Curator)PTCSC1 was added to Inherited non-medullary thyroid cancerpanel. Sources: Literature