Inherited non-medullary thyroid cancer
Gene: PTCSC3
PTCSC3 (papillary thyroid carcinoma susceptibility candidate 3 (non-protein coding))
EnsemblGeneIds (GRCh38): ENSG00000259104
EnsemblGeneIds (GRCh37): ENSG00000259104
OMIM: 614821, Gene2Phenotype
PTCSC3 is in 1 panel
EnsemblGeneIds (GRCh38): ENSG00000259104
EnsemblGeneIds (GRCh37): ENSG00000259104
OMIM: 614821, Gene2Phenotype
PTCSC3 is in 1 panel
1 review
Emma Woodward (Manchester Centre for Genomic Medicine)
SNP association only. insufficient evidence for clinical utility.
Jendrzejewski, J., He, H., Radomska, H. S., Li, W., Tomsic, J., Liyanarachchi, S., Davuluri, R. V., Nagy, R., de la Chapelle, A. The polymorphism rs944289 predisposes to papillary thyroid carcinoma through a large intergenic noncoding RNA gene of tumor suppressor type. Proc. Nat. Acad. Sci. 109: 8646-8651, 2012.Created: 13 Jun 2017, 2:52 p.m.
Details
- Mode of Inheritance
- Unknown
- Sources
-
- Literature
- Phenotypes
-
- papillary thyroid carcinoma
- OMIM
- 614821
- Clinvar variants
- Variants in PTCSC3
- Penetrance
- Complete
- Publications
- Panels with this gene
History Filter Activity
7 Aug 2017, Gel status: 0
panel promoted to version 1
Sarah Leigh (Genomics England Curator)All genes have been reviewed and the reviews evaluated. 07.08.2017
18 May 2017, Gel status: 0
Added New Source
Sarah Leigh (Genomics England Curator)PTCSC3 was added to Inherited non-medullary thyroid cancerpanel. Sources: Literature
18 May 2017, Gel status: 0
Created
Sarah Leigh (Genomics England Curator)PTCSC3 was created by sleigh