Inherited bleeding disorders
Gene: FGGEnsemblGeneIds (GRCh38): ENSG00000171557
EnsemblGeneIds (GRCh37): ENSG00000171557
OMIM: 134850, Gene2Phenotype
FGG is in 4 panels
2 reviews
Louise Daugherty (Genomics England Curator)
Mode of inheritance
BOTH monoallelic and biallelic, autosomal or pseudoautosomal (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
Phenotypes
Fibrinogen deficiency
BRIDGE consortium (NIHRBR-RD)
Mode of inheritance
BOTH monoallelic and biallelic, autosomal or pseudoautosomal (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
Phenotypes
Fibrinogen deficiency
Variants in this GENE are reported as part of current diagnostic practice
Details
- Mode of Inheritance
- BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
- Sources
-
- Other
- Radboud University Medical Center, Nijmegen
- Expert Review Green
- BRIDGE Study Tier 1 Gene
- Phenotypes
-
- Fibrinogen deficiency
- Dysfibrinogenemia,congenital,616004
- Dysfibrinogenemia, congenita
- Hypodysfibrinogenemia
- OMIM
- 134850
- Clinvar variants
- Variants in FGG
- Penetrance
- Complete
- Panels with this gene
History Filter Activity
panel promoted to version 1
Louise Daugherty (Genomics England Curator)Revised 19 December 2016
Set Mode of Inheritance
Louise Daugherty (Genomics England Curator)Mode of inheritance for FGG was changed to BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
Set Mode of Inheritance, Added New Source
Ellen McDonagh (Genomics England Curator)FGG was added to Inherited bleeding disorderspanel. Source: Radboud University Medical Center, Nijmegen FGG was added to Inherited bleeding disorderspanel. Source: Other Model of inheritance for gene FGG was set to BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Set Mode of Inheritance, Added New Source
Louise Daugherty (Genomics England Curator)FGG was added to Inherited bleeding disorderspanel. Source: Expert Review Green Model of inheritance for gene FGG was set to BOTH monoallelic and biallelic, autosomal or pseudoautosomal (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
Added New Source
Ellen McDonagh (Genomics England Curator)FGG was added to Inherited bleeding disorderspanel. Sources: BRIDGE Study Tier 1 Gene
Created
Ellen McDonagh (Genomics England Curator)FGG was created by ellenmcdonagh