1. Panels
  2. Structural basal ganglia disorders
  3. MT-ND1
STRs in panel
Prev Next
Regions in panel
Prev Next

Structural basal ganglia disorders

Gene: MT-ND1

Green List (high evidence)
MT-ND1 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1)
EnsemblGeneIds (GRCh38): ENSG00000198888
EnsemblGeneIds (GRCh37): ENSG00000198888
OMIM: 516000, Gene2Phenotype
MT-ND1 is in 11 panels

5 reviews

Carl Fratter (Oxford University Hospitals NHS Trust)

Green List (high evidence)

Mode of inheritance
MITOCHONDRIAL

Variants in this GENE are reported as part of current diagnostic practice

Created: 5 Nov 2017, 2:48 a.m.

Panel version: Imported from "Mitochondrial disorders" panel version 0

Sarah Leigh (Genomics England Curator)

Comment on list classification: Green on Version 1 Mitochondrial disorders panel
Created: 2 Mar 2017, 1:48 p.m.
Created: 2 Mar 2017, 1:44 p.m.

Panel version: 0.71

Manju Kurian (UCL-Institute of Child Health)

Green List (high evidence)

Mode of inheritance
MITOCHONDRIAL

Created: 1 Mar 2017, 5:01 p.m.

Panel version: 0.55

Ellen McDonagh (Genomics England Curator)

Comment on list classification: Both reviewers agree this gene should be promoted from red to green.
Created: 10 Feb 2016, 12:52 p.m.
Created: 10 Feb 2016, 12:52 p.m.

Panel version: Imported from "Mitochondrial disorders" panel version 0.200

Shamima Rahman (UCL Institute of Child Health)

Green List (high evidence)

Created: 8 Feb 2016, 10:32 a.m.

Panel version: Imported from "Mitochondrial disorders" panel version 0.37

History Filter Activity

18 Oct 2023, Gel status: 3

Removed Tag

Achchuthan Shanmugasundram (Genomics England Curator)

Tag limit of detection for heteroplasmic variants is not validated for WGS testing was removed from gene: MT-ND1.

12 Sep 2023, Gel status: 3

Added Tag

Achchuthan Shanmugasundram (Genomics England Curator)

Tag limit of detection for heteroplasmic variants is not validated for WGS testing tag was added to gene: MT-ND1.

9 May 2022, Gel status: 3

Added Tag

Eleanor Williams (Genomics England Curator)

Tag gene-checked tag was added to gene: MT-ND1.

16 Mar 2017, Gel status: 4

panel promoted to version 1

Sarah Leigh (Genomics England Curator)

promoted 16/03/2017

2 Mar 2017, Gel status: 4

Gene classified by Genomics England curator

Sarah Leigh (Genomics England Curator)

This gene has been classified as Green List (High Evidence).

1 Mar 2017, Gel status: 0

Added New Source

Manju Kurian (UCL-Institute of Child Health)

MT-ND1 was added to Structural basal ganglia disorderspanel. Sources: Literature

1 Mar 2017, Gel status: 0

Created

Manju Kurian (UCL-Institute of Child Health)

MT-ND1 was created by Manju