Diabetes with additional phenotypes suggestive of a monogenic aetiology
Gene: ABCC8
Mode of inheritance sources: Illumina BIALLELIC, autosomal or pseudoautosomal for Permanent Neonatal Diabetes Mellitus, MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown for Transient Neonatal Diabetes, Dominant. UKGTN MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown for Permanent neonatal diabetes mellitus; transient neonatal diabetes (Dominant) and DIABETES MELLITUS, NONINSULIN-DEPENDENT.Created: 17 Jul 2015, 3:02 p.m.
Mode of inheritance
BOTH monoallelic and biallelic, autosomal or pseudoautosomal
25th July 2016: Panel revised acccording to expert review, further evidence sources and comparison with the Familial Diabetes version 1 panel. Promoted to version 1.
This gene has been classified as Green List (High Evidence).
Model of inheritance for gene ABCC8 was changed to BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Model of inheritance for gene ABCC8 was changed to BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Model of inheritance for gene ABCC8 was changed to BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Model of inheritance for gene ABCC8 was changed to BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Model of inheritance for gene ABCC8 was changed to BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Model of inheritance for gene ABCC8 was changed to BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Model of inheritance for gene ABCC8 was changed to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Model of inheritance for gene ABCC8 was changed to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
ABCC8 was added to Diabetes with additional phenotypes suggestive of a monogenic aetiologypanel. Sources: UKGTN
Model of inheritance for gene ABCC8 was changed to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Model of inheritance for gene ABCC8 was changed to BIALLELIC, autosomal or pseudoautosomal
ABCC8 was added to Diabetes with additional phenotypes suggestive of a monogenic aetiologypanel. Sources: Illumina TruGenome Clinical Sequencing Services
ABCC8 was added to Diabetes with additional phenotypes suggestive of a monogenic aetiologypanel. Sources: Radboud University Medical Center, Nijmegen