Diabetes with additional phenotypes suggestive of a monogenic aetiology

Gene: ALMS1

Green List (high evidence)

ALMS1 (ALMS1, centrosome and basal body associated protein)
EnsemblGeneIds (GRCh38): ENSG00000116127
EnsemblGeneIds (GRCh37): ENSG00000116127
OMIM: 606844, Gene2Phenotype
ALMS1 is in 26 panels

1 review

Sian Ellard (University of Exeter Medical School)

Green List (high evidence)

History Filter Activity

25 Jul 2016, Gel status: 4

panel promoted to version 1

Ellen McDonagh (Genomics England Curator)

25th July 2016: Panel revised acccording to expert review, further evidence sources and comparison with the Familial Diabetes version 1 panel. Promoted to version 1.

29 Jun 2016, Gel status: 4

Set Phenotypes

Ellen McDonagh (Genomics England Curator)

Phenotypes for ALMS1 were set to Alstrom syndrome

29 Jun 2016, Gel status: 4

Gene classified by Genomics England curator

Ellen McDonagh (Genomics England Curator)

This gene has been classified as Green List (High Evidence).

7 Jun 2016, Gel status: 4

Gene classified by Genomics England curator

Chris Boustred (Genomics England)

This gene has been classified as Green List (High Evidence).

7 Jun 2016, Gel status: 0

Set Mode of Inheritance

Chris Boustred (Genomics England)

Mode of inheritance for ALMS1 was changed to BIALLELIC, autosomal or pseudoautosomal

17 Aug 2015, Gel status: 0

Added New Source

Ellen McDonagh (Genomics England Curator)

ALMS1 was added to Diabetes with additional phenotypes suggestive of a monogenic aetiologypanel. Sources: Eligibility statement prior genetic testing